Anthocyane – Therapie

Anthocyane haben in der wissenschaftlichen Forschung zunehmend Aufmerksamkeit auf sich gezogen, insbesondere dank ihrer antioxidativen und antiinflammatorischen (antientzündlichen) Eigenschaften, die das Potenzial für die Behandlung und Prävention zahlreicher Krankheiten aufzeigen.

Anthocyane in der Therapie:

• Glaukom [1]
• Kardiovaskuläre Erkrankungen (Herz- und Gefäßerkrankungen) [2-11]
• Neurodegenerative Erkrankungen [3, 12,13]
• Nicht-alkoholische Fettlebererkrankung [14]
• Tumorerkrankungen [1, 15-17]
• Adipositas [18]

Literatur

1. Ohguro H, Ohguro I, Yagi S. Effects of black currant anthocyanins on intraocular pressure in healthy volunteers and patients with glaucoma. J Ocul Pharmacol Ther. 2013 Feb;29(1):61-7.
2. Gonçalves AC, Nunes AR, Falcão A, Alves G, Silva LR. Dietary Effects of Anthocyanins in Human Health: A Comprehensive Review. Pharmaceuticals (Basel). 2021 Jul 18;14(7):690. doi: 10.3390/ph14070690.
3. Kalt W, Cassidy A, Howard LR, Krikorian R, Stull AJ, Tremblay F, Zamora-Ros R. Recent Research on the Health Benefits of Blueberries and Their Anthocyanins. Adv Nutr. 2020 Mar 1;11(2):224-236.
4. Mattioli R, Francioso A, Mosca L, Silva P. Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases. Molecules. 2020 Aug 21;25(17):3809.
5. Wallace TC, Slavin M, Frankenfeld CL. Systematic Review of Anthocyanins and Markers of Cardiovascular Disease. Nutrients. 2016 Jan 9;8(1):32.
6. Curtis PJ, van der Velpen V, Berends L, Jennings A, Feelisch M, Umpleby AM, Evans M, Fernandez BO, Meiss MS, Minnion M, Potter J, Minihane AM, Kay CD, Rimm EB, Cassidy A. Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial. Am J Clin Nutr. 2019 Jun 1;109(6):1535-1545.
7. Wallace TC. Anthocyanins in cardiovascular disease. Adv Nutr. 2011 Jan;2(1):1-7.
8. Curtis PJ, van der Velpen V, Berends L, Jennings A, Feelisch M, Umpleby AM, Evans M, Fernandez BO, Meiss MS, Minnion M, Potter J, Minihane AM, Kay CD, Rimm EB, Cassidy A. Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial. Am J Clin Nutr. 2019 Jun 1;109(6):1535-1545.
9. Curtis PJ, Kroon PA, Hollands WJ, Walls R, Jenkins G, Kay CD, Cassidy A. Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks. J Nutr. 2009 Dec;139(12):2266-71.
10. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res. 2021 Jun;35(6):3236-3245.
11. Li D, Zhang Y, Liu Y, Sun R, Xia M. Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and prevents insulin resistance in diabetic patients. J Nutr. 2015 Apr;145(4):742-8.
12. García-Cordero J, Pino A, Cuevas C, Puertas-Martín V, San Román R, de Pascual-Teresa S. Neurocognitive Effects of Cocoa and Red-Berries Consumption in Healthy Adults. Nutrients. 2021 Dec 21;14(1):1.
13. Aarsland D, Khalifa K, Bergland AK, Soennesyn H, Oppedal K, Holteng LBA, Oesterhus R, Nakling A, Jarholm JA, de Lucia C, Fladby T, Brooker H, Dalen I, Ballard C. A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia. Am J Geriatr Psychiatry. 2023 Feb;31(2):141-151.
14. Masnadi Shirazi K, Shirinpour E, Masnadi Shirazi A, Nikniaz Z. Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial. BMC Complement Med Ther. 2021 Nov 19;21(1):283.
15. Li W, Peng C, Zhaojie L, Wei W. Chemopreventive and therapeutic properties of anthocyanins in breast cancer: A comprehensive review. Nutr Res. 2022 Nov;107:48-64.
16. Nascimento RPD, Machado APDF. The preventive and therapeutic effects of anthocyanins on colorectal cancer: A comprehensive review based on up-to-date experimental studies. Food Res Int. 2023 Aug;170:113028.
17. de Sousa Moraes LF, Sun X, Peluzio MDCG, Zhu MJ. Anthocyanins/anthocyanidins and colorectal cancer: What is behind the scenes? Crit Rev Food Sci Nutr. 2019;59(1):59-71.
18. Lee YM, Yoon Y, Yoon H, Park HM, Song S, Yeum KJ. Dietary Anthocyanins against Obesity and Inflammation. Nutrients. 2017 Oct 1;9(10):1089.