Epigallocatechingallat – Prävention

Aus Studienergebnissen geht hervor, dass es sich beim Epigallocatechingallat um eine der vielversprechendsten gesundheitsfördernden Substanzen handelt.

Epigallocatechingallat (EGCG) in der Prävention:

• Adipositas [1, 2]
• Atherosklerose (Arteriosklerose; Arterienverkalkung) [3]
• Bösartige Neubildung der Brustdrüse (Mammakarzinom/Brustkrebs) [4, 5]
• Bösartige Neubildung Cervix uteri (Cervixkarzinom/Gebärmutterhalskrebs) [6]
• Bösartige Neubildung der Prostata (Prostatakarzinom/Prostatakrebs) [7]
• Dermatitis (entzündliche Reaktion der Haut) [8]
• Erkrankungen der oberen Atemwege [9]
• Förderung der allgemeinen Gesundheit und des Wohlbefindens [10-12]
• Apoplex (Hirninfarkt; Schlaganfall) [6]
• Xerosis cutis (Xerodermie/Trockene Haut) [13]

Literatur

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2. Kovacs EM, Lejeune MP, Nijs I, Westerterp-Plantenga MS. Effects of green tea on weight maintenance after body-weight loss. Br J Nutr. 2004 Mar;91(3):431-7.
3. Kuriyama S, Shimazu T, Ohmori K, Kikuchi N, Nakaya N, Nishino Y, Tsubono Y, Tsuji I. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. JAMA. 2006 Sep 13;296(10):1255-65.
4. Dostal AM, Samavat H, Bedell S, Torkelson C, Wang R, Swenson K, Le C, Wu AH, Ursin G, Yuan JM, Kurzer MS. The safety of green tea extract supplementation in postmenopausal women at risk for breast cancer: results of the Minnesota Green Tea Trial. Food Chem Toxicol. 2015 Sep;83:26-35.
5. Seely D, Mills EJ, Wu P, Verma S, Guyatt GH. The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis. Integr Cancer Ther. 2005 Jun;4(2):144-55.
6. Ahn WS, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions. Eur J Cancer Prev. 2003 Oct;12(5):383-90.
7. Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A. Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res. 2006 Jan 15;66(2):1234-40.
8. Zhao H, Zhu W, Zhao X, Li X, Zhou Z, Zheng M, Meng X, Kong L, Zhang S, He D, Xing L, Yu J. Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial. JAMA Dermatol. 2022 Jul 1;158(7):779-786.
9. Furushima D, Nishimura T, Takuma N, Iketani R, Mizuno T, Matsui Y, Yamaguchi T, Nakashima Y, Yamamoto S, Hibi M, Yamada H. Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial. Nutrients. 2019 Dec 18;12(1):4.
10. Khan N, Mukhtar H. Tea Polyphenols in Promotion of Human Health. Nutrients. 2018 Dec 25;11(1):39.
11. Kochman J, Jakubczyk K, Antoniewicz J, Mruk H, Janda K. Health Benefits and Chemical Composition of Matcha Green Tea: A Review. Molecules. 2020 Dec 27;26(1):85.
12. Chowdhury A, Sarkar J, Chakraborti T, Pramanik PK, Chakraborti S. Protective role of epigallocatechin-3-gallate in health and disease: A perspective. Biomed Pharmacother. 2016 Mar;78:50-59.
13. Puch F, Samson-Villeger S, Guyonnet D, Blachon JL, Rawlings AV, Lassel T. Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. Exp Dermatol. 2008 Aug;17(8):668-74.